The Denaturation of Lactic Dehydrogenases
نویسندگان
چکیده
منابع مشابه
The Denaturation of Lactic Dehydrogenases. I. the Effect of Sodium Dodecyl Sulfate.
Recent studies have indicated (1,2) that lactic dehydrogenases are composed of four subunits. However, little is known about the nature of the forces holding the subunits together. Recently, Di Sabato, Pesce, and Kaplan (3) demonstrated the absence of disulfide bridges in these enzymes. The association, at least in part, may be due to charge groups outside the pH range from 6 to 9 (4, 5). Appel...
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Until about 1957 the L(+)-lactic dehydrogenase of aerobic cells was the only enzyme concerned with lactate oxidation known to occur in yeast. At that time, essentially simultaneously and independently, four laboratories discovered the existence of a second lactic dehydrogenase in yeast, which, in distinction to the L enzyme, occurred in anaerobic cells and reacted with ferricyanide but not cyto...
متن کاملThe Lactic Dehydrogenases of Yeast
The n-lactic cytochrome reductase of yeast, discovered some 4 years ago (5), is a zinc-flavoprot,ein present in the respiratory granules of aerobic yeast. Its substrate specificity is highly restricted in that it oxidizes only D( -)-lactate and n-a-hydroxybutyrate and reduces only phenazine methosulfate and cytochrome c (6, 7). In these respects and many others, it differs from the L(+)-lactic ...
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Walker, Hazel (University of Georgia, Athens), and R. G. Eagon. Lactic dehydrogenases of Pseudomonas natriegens. J. Bacteriol. 88:25-30. 1964.-Lactic dehydrogenases specific for d- and l-lactate were demonstrated in Pseudomonas natriegens. The l-lactic dehydrogenase showed considerable heat stability, and 40% of the activity remained in extracts after heating at 60 C for 10 min. An essential th...
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Stereospecificity of Some Invertebrate Lactic Dehydrogenases by Mary Jacobs Scheid 1. It has been assumed that only among unicellular organisms did nicotin¬ amide adenine dinucleotide (NAD)-linked lactic dehydrogenases occur. All higher animals were thought to possess Lspecific lactic dehydro¬ genases. It was discovered recently, however, that many species of invertebrates possess lactic dehydr...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1965
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)97539-3